I nominate the following.
Ken Marino: in a nice surreal comedy where he can flex his incredible comedic/dramatic skills. Even though he's been on TV for years, I didn't really notice him until Reaper — the show was totally goofball, but not Ken and the way he portrayed his gay fallen angel, going from sweet to goofy to frighteningly evil in a mind's blur. He deserves so much more than an occasional anonymous bit part in shows like Greek. BTW, did I mention he's totally hot?
Christina Hendricks: I really liked her in Firefly, so how about a sci-fi adventure dramedy where her curves can literally kick some male ass.
John Slattery: in a comedy where he can play a total goofball who always gets the girl.
Conchata Ferrell: in a drama because this lady can seriously act. Seeing her sleepwalk through Two and a Half Men breaks my heart.
Harriet Sansom Harris: I really miss seeing her on TV; while she was delicious as Bebe in Frasier, I want to see her in a drama.
Wayne Knight: I don't care what he's in, he's always so great. Whether as the hateable Newman in Seinfeld or the lovable cop in 3rd Rock, he can always make you laugh.
Me. I'm not an actor, but I feel like I really need to be in a nice comedy. One in which you meet nice new people in nice cozy situations and everything always works out every half hour, where there's always a yummy catering truck and someone does my hair and make-up on a daily basis.